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SULFONILUREIAS
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Será que são todas iguais? As evidências mostram que não! Confere essa informação aqui!
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Existem outras opções com baixo risco de hipoglicemia, como glipizida e glimepirida.
Já viu algum caso de hipoglicemia secundário a sulfoniluréia? Consegue encontrar gliclazida na sua região?
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REFERENCIAS:
1. TESSIER, D. et al. Glibenclamide vs gliclazide in type 2 diabetes of the elderly. Diabetic medicine, v. 11, n. 10, p. 974-980, 1994.
2. COLAGIURI, Stephen et al. The place of gliclazide MR in the evolving type 2 diabetes landscape: a comparison with other sulfonylureas and newer oral antihyperglycemic agents. Diabetes research and clinical practice, v. 143, p. 1-14, 2018.
3. SCHERNTHANER, G. et al. GUIDE study: double‐blind comparison of once‐daily gliclazide MR and glimepiride in type 2 diabetic patients. European journal of clinical investigation, v. 34, n. 8, p. 535-542, 2004.
4. SCHOPMAN, Josefine E. et al. The incidence of mild and severe hypoglycaemia in patients with type 2 diabetes mellitus treated with sulfonylureas: a systematic review and meta‐analysis. Diabetes/metabolism research and reviews, v. 30, n. 1, p. 11-22, 2014.
5. HOLSTEIN, Andreas; PLASCHKE, Armin; EGBERTS, Eick‐Hartwig. Lower incidence of severe hypoglycaemia in patients with type 2 diabetes treated with glimepiride versus glibenclamide. Diabetes/metabolism research and reviews, v. 17, n. 6, p. 467-473, 2001.
6. GANGJI, Azim S. et al. A systematic review and meta-analysis of hypoglycemia and cardiovascular events: a comparison of glyburide with other secretagogues and with insulin. Diabetes care, v. 30, n. 2, p. 389-394, 2007.
7. SHORR, Ronald I. et al. Incidence and risk factors for serious hypoglycemia in older persons using insulin or sulfonylureas. Archives of internal medicine, v. 157, n. 15, p. 1681-1686, 1997.

Glibenclamida, Gliclazida,